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This activation: Promotes directed cell migration toward injury sites Enhances cellular outgrowth from damaged tissue edges Improves cell survival during the stressful healing process Facilitates proper tissue organization This mechanism is particularly relevant for tendon and ligament healing, where cellular organization and proper fiber alignment are critical for functional recovery

If a cells DNA is its operating system, then the epigenome is the software

[DOI] [PMC free article] [PubMed] [Google Scholar] 670.Perry R.J., Samuel V.T., Petersen K.F., Shulman G.I

No randomization was used to allocate animals to experimental groups, and investigators were not blinded to the group allocation during experiments or outcome assessments