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Indeed, the thermolabile MTHFR defect and heterozygosity for CBS deficiency might increase vascular disease risk by respectively increasing the amounts of dietary folate and vitamin B 6 that are needed to prevent hyperhomocysteinemia
Potential adverse effects related to chronic GH/IGF-1 elevation represent an important theoretical concern
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The data shown reflect the detection of their corresponding NEM adducts (for example, NEM-cystine, NEM-cysteinylglycine and NEM-GSH)