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Individuals with malabsorption conditions, severe deficiency, or those who havent responded to oral supplements typically benefit most from injections

For instance, some individuals may experience side effects or have an immune system response that causes them to feel unwell temporarily

Food intake does not significantly affect their absorption or effectiveness

Meta-analysis Meta-analysis was performed using the R statistical program, R version 4.4.2 (The R Foundation for Statistical Computing, Wirtschaftsuniversitt Wien, Vienna, Austria) (Sterne et al., 2016