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Cutting-edge research has highlighted the successful use of groundbreaking sustained-release technology known as the port delivery system (PDS)

The serious gastrointestinal side effects of long-term administration of NSAIDs including ibuprofen, limit their clinical applicability [17]

Its relevance to neuropathy is most direct in the metabolic neuropathies, particularly diabetic peripheral neuropathy, where impaired glucose metabolism, insulin resistance, and mitochondrial dysfunction all contribute to nerve damage