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Upon cellular stress, characteristic of ASD [158], ROS production and elevated intracellular Ca 2+ concentration trigger mPTP opening leading to mitochondrial membrane permeabilization (MMP) [181], initiating apoptosis and necrosis [269], and regulating the activity of autophagy [270, 271]

Cytogenotoxicity of Cymbopogon citratus (DC) stapf (lemon grass) aqueous extracts in vegetal test systems

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When retatrutide binds to GLP-1 receptors, it stimulates insulin release from the pancreas, reduces glucagon secretion, delays gastric emptying, and suppresses appetite through direct signaling to the brain