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This makes nicotine withdrawal an important target for intervention for smokers with a mental illness.[14] Starting the Journey to Stop Smoking Patients with a psychiatric illness and comorbid nicotine dependence are dying 25 years younger than the general population, from smoking-related illnesses such as heart and lung disease.[15] Understanding why these patients smoke, becoming dependent on nicotine, and what we can do to encourage smoking cessation would help prevent these premature mortalities

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