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This toxicity is largely attributed to the aberrant association of PQC network components and other metastable proteins with these aggregates, including molecular chaperones, ubiquitin conjugates, proteasome subunits, the transcription coactivator cAMP response elementbinding protein (CREB)binding protein (CBP), the ATPase valosincontaining protein (VCP)/p97, and nonexpanded wild-type ATXN3 [53,54,55,56,57,58]
Ragonese F, Monarca L, De Luca A, et al
While compared to DEX, there was a decrease in brain MDA levels with DEX/SILY 140, DEX/SILY 280, DEX/SERT/SILY 140, and DEX/SERT/SILY 280
Oxidative damage-induced inflammation initiates age-related macular degeneration