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In this context, a sub-multiplicative interaction refers to a joint effect that is greater than additive but less than multiplicative, as defined by Laurier et al

These outcomes suggest PDAs potential role as a powerful adjunctive option in both pre- and post-surgical care strategies

K.HattoriS.-i.et al

Consistent with this notion, under conditions of cysteine starvation, the GSH-catabolizing enzyme CHAC1 mobilizes cysteine to sustain mitochondrial Fe-S cluster biogenesis and respiratory function

This mechanism suggests BPC-157 functions as a cellular sensitizer to endogenous growth factors rather than as a direct growth factor itself