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[12] [13] In theory, supplementation may help maintain cartilage structure and provide modest symptomatic relief for joint pain, though any benefits are symptomatic rather than disease-modifying

To avoid this, its recommended to take L-carnitine with food

Additional neurotrophic factors, including insulin-like growth factor 1 (IGF-1) and nerve growth factor (NGF), exert complementary effects by regulating cellular metabolism, promoting anti-apoptotic pathways, and enhancing myelination [239, 240]