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Bupropion is metabolized to its active metabolite, hydroxybupropion (HB), by the genetically polymorphic cytochrome P450 2B6 (CYP2B6) enzyme [130]

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But gloves and new rules appeared to curb the animality sufficiently to allow a titillating sense of danger inside safe and civilized boundaries. Electric lighting, as Gorn also points out, also helped transform the boxing ring from disreputable diversion into commercially raffish evening spectacle.[417] The new conditions, of course, were intended for the benefit of promoters, not fighters

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