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This was established as an important research question to be funded as part of the James Lind Alliance priority-setting partnership with the Pernicious Anaemia Society

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Animal studies have validated this efficacy, showing that TETA therapy enhances cardiac pumping efficiency and normalizes the levels of copper, copper-binding proteins, and CCO in the myocardial tissue [51]

Echocardiography is also used to determine the left ventricular ejection fraction, an objective measure of the heart's pumping ability (31)