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[20] Definition [edit] Nicotine dependence is defined as a neurobiological adaptation to repeated drug exposure that is manifested by highly controlled or compulsive use, the development of tolerance, experiencing withdrawal symptoms upon cessation including cravings, and an inability to quit despite harmful effects

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Table 1 presents the demographics of the 101 patients who participated

Living in New York, especially: The week before it came out, I was walking down the street, going to my normal coffee shop and the week after, Im getting recognized