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Anti-apoptotic proteins form heterodimers with pro-apoptotic proteins through the BH1-3 domains, thereby inhibiting their pro-apoptotic activity (61)
Batch: GF-IPA10-B241 Key analytical results include: Assay Content: 10.40 mg Identification Retention Time: 0.981 Identification Spectrum: 996 Purity: greater than 99.8 percent Bacterial Endotoxins: below 0.001 EU per mg Total Aerobic Microbial Count: not detected Total Yeast and Mold Count: not detected Independent heavy metal screening confirmed no detectable levels of arsenic, cadmium, cobalt, lead, nickel, mercury or vanadium
Antibodies Primary antibodies: -actin (A5441, Sigma-Aldrich), -CSE (ab189916, Abcam), -ETHE1 (GTX115707, GeneTex), -GPX4 (ab125066, Abcam), -MPST (PA5-51548, Thermo Fisher Scientific), -SQR (ab71978, Abcam) and -xCT (26864-1-AP, Proteintech)
For instance, tumor cells that overexpress FSP1, a GPX4-independent ferroptosis suppressor, exhibit relative resistance to GPX4 inhibitors
