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NTP, 2007)

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A different method to measure the nicotine dose is to monitor the blood plasma levels during one day of controlled tobacco consumption (snus use or smoking) and then compare the nicotine uptake curves with the corresponding curve for a reference product with a known nicotine dose

These studies demonstrate that oxidative DNA damage (8-oxoG) is elevated and oxidative DNA repair (Ogg1 and Ape1) is altered in the brain of SHS exposed mice, as well as activation of reactive astrocytes

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