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Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes

Elevated plasma levels of TMAO are associated with increased risk of cardiovascular disease.Formal Name: N,N-dimethyl-methanamine, N-oxide

doi: 10.1007/s00281-019-00741-8 199 ReinckeSMvon WardenburgNHomeyerMAKornauHCSpagniGLiLYet al

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The researchers carried out a mediation analysis, a statistical technique used to determine whether a particular factor, in this case TMAO metabolites, influenced the incidence of atherosclerotic cardiovascular disease