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The study suggests that the health benefits of e-cigarettes are only apparent from the complete replacement of cigarettes with e-cigarettes but not from dual use with ongoing smoking (63)

Previous reports of this and other studies 13 , 14 , 17 , 21 , 22 have reviewed the associations of smoking with many specific causes of death and considered the reasons for them, leading to the conclusion that in this study the substantial differences between smokers and non-smokers in overall mortality are due chiefly to the causal effects of smoking