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This chapter also investigates various mechanisms of toxicity from the perspectives of pulmonary, inflammation, oxidative stress, DNA damage, apoptosis, transcriptome alterations, and epithelial-mesenchymal transition (EMT), all of which are directly linked to the effects of e-cigs

The potential hazard was first identified in a 2014 study that found diacetyl in nearly 70 percent of the 160 e-cigarette products tested

Historical perspective on heart function: the FrankStarling Law

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