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derivatives may be effective at lower concentrations)) Clinical evidence Tetrahexyldecyl ascorbate, a lipid-soluble derivative of ascorbic acid, has been shown to have superior stability and skin-mimicking properties compared to native ascorbic acid

Um H-C, Jang J-H, Kim D-H et al (2011) Nitric oxide activates Nrf2 through S-nitrosylation of Keap1 in PC12 cells

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The inflammatory signaling in microglia is primarily mediated through classical pathways such as TLR4/NF-B and JAK/STAT, which are crucial for sustaining this activation (174, 175)