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By infusing the nutrients intravenously, we bypass the gastrointestinal (GI) system where the acidic environment of the stomach, difficulty of intestinal absorption, and liver metabolism may lead to as little as 20-30% absorption of oral supplements

The compound's selectivity profile minimizes concerns about off-target effects, but investigators should consider potential interactions with other NAD+-modulating interventions or compounds that affect methylation metabolism

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& Whiteley, W

Critical role of PepT1 in promoting colitis-associated cancer and therapeutic benefits of the anti-inflammatory pept1-mediated tripeptide KPV in a murine model