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"Any product that brings both pleasures and problems requires a balancing act," the Times says, which means "personal freedom" must be curtailed to protect "public health." That formulation is inherently paternalistic, since the "public health" burden to which the Times refers is borne mainly by cannabis consumers themselves

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The qPCR was run using total cDNA combined with AceQ SYBR qPCR Master Mix (Q111-03, Vayzme, Nanjing, China) and primers (Supplementary Table 2) on a Bio-Rad thermal cycler

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In addition all participants were offered behavioural support during their efforts to quit