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10.1016/j.jalz.2019.07.002 Alzheimers Dement

Prophylactic protection against Soman with PB & the Gulf War Syndrome: Because of its rapid aging, the US military employed the use of oral pyridostigmine (PB) to ~250,000 soldiers as a form of prophylactic protection for soldiers in combat situations where exposure to soman was likely

4 Nrf2 binds antioxidant response elements (AREs) and induces phase II detoxification enzymes, including glutathione S transferases (GSTs), nicotinamide adenine dinucleotide (phosphate) hydrogen [NAD(P)H] quinone oxidoreductase 1 (NQO1), heme oxygenase 1 (HO-1), and enzymes for GSH synthesis

Li J, Li M, Ge Y, Chen J, Ma J, Wang C, et al