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Withdrawal also causes stress, which can in turn lead to nausea and constipation

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The ease of over-consuming nicotine with Juul makes this likely, especially in light of reports of teenagers binging on Juul to the point of rapid addiction and behavioral consequences. One reason why Juul delivers more nicotine than other e-cigarettes has to do with the introduction of acidified nicotine salts

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However, among middle school students -- in grades 6 to 8 -- there was an increase with 6.6% in 2023 saying they currently used at least one tobacco product, up from 4.5% in 2022