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doi: 10.37275/bsm.v6i11.603 126

Specificity protein 1-mediated acsl4 transcription promoted the osteoarthritis progression through suppressing the ferroptosis of chondrocytes

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Necroptosis is usually triggered via Toll-like receptors or death receptors that include TNF receptor-1 (TNFR1) 49 acting via RIPK1 to sequentially activate RIPK3 and MLKL