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The effectiveness of the TJs results from the strong linkage of trans membranal claudins and occludins to intracellular actin and the cytoskeleton induced by cytoplasmic scaffolding proteins, zonula occludentes (ZO-1, 2, and 3) (Pandit et al., 2020)

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Misconceptions about nicotine, such as the belief that it can be controlled without leading to addiction, are widespread