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Should we encourage existing smokers to use e-cigarettes to help them stop smoking, even if this means they continue using nicotine long-term

Deganello, A.M., Retailleau, L., Boreave, A., and Giroir-Fendler, A., Appl

The complete NCCN Guidelines for Smoking Cessation are not printed in this issue of JNCCN but can be accessed online at NCCN.org

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This provides a solid link to TS-dependent impairment of BBB function whereas cigarette smoke extracts have been shown to act as a powerful activator of immune/inflammatory response pathways altering the integrity/function of the BBB [13, 14]