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The regulation of mitochondrial biogenesis generally begins with AMP-activated protein kinase (AMPK), a key factor in sensing energy status (Hardie et al., 2012)

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For accurate and up-to-date information on the regulations governing nicotine pouches, Australian consumers can consult the TGA and other relevant government resources

15 Additionally, cigarettes contain over 7,000 potentially harmful chemicals, some of which are known to cause cancer, including formaldehyde, benzene, polonium-210 and vinyl chloride

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