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[97] study indicated that co-cultured human pulmonary vascular endothelial cells (HPVECs) with different concentrations of CSE (0%, 0.1%, 1% and 10%) significantly promoted cell apoptosis, increased caspase-3 activity, upregulated Bax expression, decreased Bcl-2 expression, and increased expression of the lncRNA MEG3

doi:10.3390/ijerph15061190 3ZhuS, ZhuangY-L, WongS, CumminsSE, TedeschiGJ

Though initial participant recruitment began in early 2021, COVID-19 restrictions and amendments to the original study ethics application to include an additional breath sample collection and exhaled carbon monoxide measurement delayed the start of in-person visits

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