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doi: 10.1016/0006-291X(85)91669-9

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Nitric oxide (NO) signaling cascade The generation of nitric oxide (NO) catalyzed by endothelial nitric oxide synthase (eNOS) plays a critical role in protecting the vascular endothelium from oxidative and inflammatory insults (27)

ISP or Intercellular Sigma Peptide, is a recently found peptide that has allowed the inhibition of inhibitory proteins found in scar tissue