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Thymosin beta-4 is a low-molecular-weight protein with a well-documented role in tissue repair processes, including wound healing, angiogenesis and peptide signaling, cellular proliferation and migration, re-epithelialization, and modulation of inflammatory responses

33 Oxidative stress is associated with the pathophysiology of cardiovascular diseases (CVDs), while antioxidants are involved in neutralizing ROS and protecting against oxidative stress

More recently, total thyroidectomy has been explored as a therapeutic option in patients with refractory symptoms, demonstrating sustained improvements in health-related quality of life compared to medical therapy