GlyT1, expressed predominantly in astrocytes and, in a circuit-dependent manner, also in neuronal compartments, acts as a key buffer for ambient glycine, thereby setting the gain of NMDAR signaling and limiting glycine spillover
Graphical abstract Keywords: Steroid metabolome, Steroid biosynthesis, Steroid metabolism, Urine metabolome, Serum metabolome Highlights The serum metabolome does not reflect steroids activated in an intracrine manner
BUILDING BLOCKS OF PATIENT CARE JOURNAL SCAN: A REVIEW OF 30 RECENT PAPERS OF IMMEDIATE CLINICAL SIGNIFICANCE, HARVESTED FROM MAJOR INTERNATIONAL JOURNALS EDITORIAL INSTRUCTIONS TO AUTHORS ROTATHON-SERIES OF SUCCESSFUL ROTA CASES LAST 2 MONTHS: AN AUDIT OUTCOMES OF AKI AUDIT IN KAUVERY ETIOLOGY, CLINICAL CHARACTERISTICS AND OUTCOMES OF PATIENTS WITH ACUTE PANCREATITIS IN KAUVERY CANTONMENT HOSPITAL (KCN), TRICHY USE OF BLOOD PRODUCTS AND STEROIDS IN THE MANAGEMENT OF DENGUE AT KAUVERY TRICHY HOSPITALS: A CLINICAL AUDIT A CLINICAL AUDIT: ON THE MANAGEMENT OF ECTOPIC PREGNANCY DIABETIC KETOACIDOSIS WITH HIGH ANION GAP METABOLIC ACIDOSIS HYPOKALEMIC PARALYSIS FROM DISTAL RENAL TUBULAR ACIDOSIS (TYPE-1) DELAYED PRESENTATION OF INTERMEDIATE SYNDROME IN A PATIENT WITH ORGANOPHOSPHORUS POISONING: A CASE REPORT SCAPULA FRACTURES: DO WE NEED TO FIX THEM
Detoxifying these metals efficiently is crucial for long-term health
Furthermore, it will explore whether, as proposed by an exponentially growing number of studies, ferroptosis signaling can serve as a therapeutic target for these patients
