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It should be noted that GCLM KO mice have systemic GSH deficiencies, ranging from 10 to 40% of normal levels depending on the tissue type 16

While a dysbiotic gut community could be the hallmark of several inflammatory diseases, the dysbiosis itself can be trigger for the unbalancing of the intestinal homeostasis and the development of inflammation [10]

237,238 Phosphorylated Drp1 translocate to the mitochondria and enhance mitochondrial fission

There was also no change in blood counts, which indicates that the decrease in HbA 1c values seen in the VD+LC group was not due to any effect on cell viability (Supplementary Table S3)

The insulin-like growth factor-binding protein superfamily