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Intraocular pressure was assessed in normal rats, and values between 13 and 19 mmHg were considered normal, in accordance with previous rat data ( To assess the effect of retrobulbar administration itself, the values were assessed before retrobulbar application, after retrobulbar application of saline (0.1 ml/each eye), BPC 157 1 g/0.1 ml saline/each eye, or L-NAME 0.5 mg/0.1 ml saline/each eye, at 1, 2, 4, 6, 8, and 10 min thereafter

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Further studies are needed to elucidate which maintenance therapy (e.g., food elimination diet, partial ED, topical/systemic immunomodulators, or monoclonal antibodies) is superior in this setting