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Single-nucleus droplets and sequencing libraries were prepared (10x Genomics)

Randomization and Blinding Participants were randomized to one of the prespecified treatment sequences for this three-period crossover trial using a computer-generated randomization list using Microsoft Excel, without stratification or blocking

Once the appropriate formula is selected, a skilled healthcare professional carefully administers the injection, typically in a muscle-rich area such as the upper arm or buttock

It reduces oxidative stress and indirectly affects melanin production