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The role of oxidative stress in the COVID-19 disease may involve recognition of the viral S-protein by angiotensin converting enzyme-2 (ACE2) receptor and pattern recognition receptors like toll-like receptors 2 and 4, and activation of transcription factors like nuclear factor kappa B, that subsequently activate nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) expression succeeded by ROS production (Kozlov et al., 2021)

B12 is an essential part of our natural biochemistry

U.de MatasM.SikstoneV.et al (2019)

However, it has recently been shown that activation of telomerase delays aging and, importantly, in mutant mice, this is achieved without increasing the incidence of cancer [292]

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