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doi:10.1007/s11096-006-9082-y

Seplveda-Lizcano, L., Arenas-Villamizar, V

With the use of the ASOs to target the SCN1A NAT, one study was effectively able to rescue the sense SCN1A gene expression, ameliorate neuronal excitability and seizures in a mouse model of DSan effect that almost entirely recapitulates the rescued phenotypes observed via CRISPRa treatment [74, 75]

In diabetes, it plays a role in insulin regulation and blood sugar control [21]

These ROS low RA T-cells are spontaneously biased to develop into IFN- and IL-17 producing pro-inflammatory T-cells, which play a central role for disease progression (58, 59)