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6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice

The Institute of Medicine reports that no adverse effects have been associated with excess vitamin B12 intake from food and supplements in healthy individuals. However, if youre not deficient in vitamin B12 to begin with or you dont address the underlying reasons you might be deficient, i.e

High levels of fibrinogen can indicate chronic inflammatory conditions and increased blood clotting formation

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