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doi: 10.1016/j.freeradbiomed.2009.08.008 67 CorralRSGuerreroNACuervoHGironesNFresnoM

A Meisel: received speaker honoraria from Alexion, argenx, Axunio, Boehringer Ingelheim, Bristol-Myers Squibb/Pfizer, Grifols, and Hormosan

The mutant BRAF exhibits constitutive activation of its kinase activity, leading to hyperactivation of MAPK signaling, which results in uncontrolled proliferation and metastasis

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