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2) The findings of the study performed by research Cangul et al consistently demonstrated that topical application of TCC significantly enhances open-wound healing in rabbits compared to zinc oxide or no treatment, particularly in the early stages of the healing process

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The absence of effects in the limited human data does not confirm long-term safety

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The main molecular mechanisms involved in the modulation of eryptosis studied to date, including intracellular calcium levels, ceramide, ROS, NO, changes in cellular energy metabolism, PS externalization, ion channel regulation, Fas-mediated signaling pathways, kinase-associated, and caspases activation, among others represent potential targets for inducing or inhibiting erythrocyte death