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For instance, blood-borne fibrin is known to activate neurotoxic innate immune responses in multiple sclerosis mice and to stimulate neurotoxic microglial programs in AD mice [130]

Wang, W

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This copper peptide gene regulation manifests in several clinically significant ways: Downregulation of Pro-Inflammatory Genes: It actively suppresses genes associated with inflammation, such as those in the IL-6 and NF-B pathways, which are major drivers of cellular aging

Jeong, J