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Both variants had not previously been described and were classified as pathogenic according to the American College of Medical Genetics (ACMG) guidelines [13]

However, during increased electron flux, superoxide production may reach a critical threshold, which may allow trafficking of superoxide anions through the mitochondrial transition pore into the cytosol, in which further damage and/or the activation of additional ROS sources may occur

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By correcting magnesium imbalances, BPC-157 may support optimal nervous system function and contribute to improved neurological health

10.3389/fphar.2021.670224 145 ZhouY.ZhangJ.GuanQ.TaoX.WangJ.LiW