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Given that the Long COVID group as a whole showed Gpx deficiency, while only a subset of patients demonstrated oxidative damage, we may infer that Gpx deficiency is the main cause of the consequent lipid and protein damage

Spermatozoa have the highest selenium content in mammalian tissues, and the need for selenium increases at the onset of spermatogenesis ( 2.5 GPX5 Glutathione peroxidase 5 (GPX5), an epididymis-specifically expressed selenium-free antioxidant enzyme, was first isolated and identified in the epididymal tissues of mice ( During epididymis transport, spermatozoa are vulnerable to intracellular and extracellular ROS attacks and rely on antioxidant scavengers synthesized by the epididymis for protection

7a and Supplementary Fig

Glutathione levels increased in the supplement group, but there was no overall improvement in diabetes markers