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This plant is used as a common remedy for the treatment of various renal diseases, including difficulty in urination, urinary infections, nephrotoxicity, and urolithiasis [30,73,74,75]

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The metabolism of D-serine is catalyzed mainly by D-amino acid oxidase (DAAO) bonding flavin adenine dinucleotide (FAD) ( Figure 1e ) ( A study demonstrated that an important rate-limiting factor in maintaining D-serine balance in the brain is L-serine synthesis via the phosphorylation pathway, which is modeled in mice with astrocyte conditions lacking Phgdh