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Conversely, strategies to enhance cytotoxic ROS levels focus on increasing ROS production to trigger oxidative stress-induced cancer cell death

The importance of folate, zinc and antioxidants in the pathogenesis and prevention of subfertility

Notably, 8-hydroxy-2-deoxyguanosine (8-OHdG), a marker of oxidative DNA damage, is elevated in liver biopsy specimens of MASLD patients, and 31 P-MRS imaging has demonstrated ATP depletion consistent with mitochondrial dysfunction [101, 102]

The review found that patients taking mucolytics were significantly more likely to be exacerbation-free during the study period compared to placebo (Peto OR 1.73, 95% CI 1.56 to 1.91)

Rahman M, Ahmad MZ, Kazmi I, Akhter S, Afzal M, Gupta G, et al