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DOI: 10.1186/s12985-015-0398-x 22

Kidney Dysfunction: While the kidneys do not directly excrete vitamin B12 efficiently, impaired renal function may lead to elevated serum B12 levels by reducing the clearance of B12-binding proteins or altering their metabolism, thereby contributing to B12 accumulation 8

We specifically focused on including the most recent findings published in the past five years

Finally, the tissue sections were washed thoroughly with PBS, counterstained with DAPI and imaged under a laser scanning confocal microscope (FV-1000, Olympus, Japan)

Cultures were performed in GAM medium (Gifu anaerobic broth, Fisher scientific, Illkirch, France), at 37C with agitation under anaerobic conditions generated by Genbag anaer (Biomerieux, Marcy lEtoile, France)