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Mechanistic studies explain why it works: the drugs travel via known vascular pathways to soak the inner ear while largely skipping the rest of the body

RAGE, a contributor to antioxidant depletion, was also increased

Maintaining the integrity of the epithelial barrier, often referred to as leaky gut protection

Excess ROS can damage cellular biomolecules, including proteins, DNA, and lipids, leading to fibroblast degeneration [23]

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