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In practice additional drugs are seldom needed with very slow benzodiazepine tapering

Hydroxyurea attenuates oxidative, metabolic, and excitotoxic stress in rat hippocampal neurons and improves spatial memory in a mouse model of Alzheimer's disease

it simply suggests that rigorous testing has to be done before it could be approved for wide spread use in humans as a standard of care for the treatment of intended diseases

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CONTRAINDICATIONS Sensitivity to cobalt and/or vitamin B 12 is a contraindication