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Mitochondrial integrity regulated by lipid metabolism is a cell-intrinsic checkpoint for T reg suppressive function

There are no published human clinical trials of Dihexa, and the closest human evidence in its drug class Athira's fosgonimeton failed its Phase 3 Alzheimer's endpoint in 2024

BPC-157 is a delicate chain of amino acids

To investigate the impact of shifting from cystine-driven to GSH-driven cysteine supply in cancer cells in an unbiased manner, we performed a multifunctional approach to pharmacological screening (MAPS) with a library of 240 metabolic inhibitors (Fig