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A pharmacokinetic study in rats found that oral administration produced substantial plasma concentrations, with a maximum concentration of 2252 ng/mL and an elimination half-life of approximately 6.9 hours

By week 68, 88.2% of those assigned to combination therapy remained on treatment

Researchers have been particularly interested in how TB-500 could serve as a simplified model to study cellular motility, tissue organization, and responses to external stimuli

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