drugs alcohol and tobacco agency Comparative risk assessment of alcohol, tobacco, cannabis other illicit using the margin of exposure approach Resources: Alcohol, Tobacco, and Other

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The resulting high is powerful but extremely short-lived, usually lasting only five to ten minutes.[2] This brief duration drives a compulsive cycle of repeated use, as people chase the initial rush with dose after dose, rapidly accelerating the path to dependence

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Instead of blocking adenosine, nicotine releases more dopamine and serotonin, which makes you alert and motivated