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Some patients find that dietary modifications alone resolve symptoms without needing additional medications, making food adjustments the preferred first step

doi:10.1016/S0968-0004(00)01712-6

High insulin level leads to a decrease in sex hormone-binding globulin (SHBG), which leads to an increase of testosterone circulation in blood, resulting in hyperandrogenemia

We demonstrated that TrkB signalling in these neurons is essential to maintain normal locomotor behaviour consistent with the initial hyperkinetic symptoms of HD and suggested that TrkB signalling deficiency may contribute effectively to HD motor symptoms 13

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